A major new study has raised concerns over the long-term effects of artificial sweeteners, finding that high consumption may be linked to faster cognitive decline and premature brain aging.
Published in the journal Neurology, the research tracked 12,772 Brazilian adults with an average age of 52 over an eight-year period. The findings revealed that participants with the highest intake of artificial sweeteners showed an estimated 62% faster rate of cognitive decline compared to low consumers. This equates to around 1.6 extra years of brain aging.
Strongest Effects in Younger Adults and Diabetics
The study noted that the impact was most pronounced among individuals under 60 and people with diabetes, suggesting that these groups may be particularly vulnerable to the neurological risks of artificial sweeteners.
Sweeteners Under Scrutiny
Among the additives most associated with faster decline were aspartame, saccharin, acesulfame-K, erythritol, sorbitol, and xylitol. One sweetener, tagatose, did not appear to have a negative effect.
These sugar substitutes are commonly found in diet sodas, flavoured waters, sugar-free yogurts, protein bars, chewing gum, and tabletop sweeteners.
Observational, But Significant
Researchers emphasized that the study was observational and did not establish direct causation. However, the results highlight the urgent need for further investigation into the long-term neurological effects of artificial sweeteners, many of which are marketed as “healthier” alternatives to sugar.
Calls for Safer Alternatives
Experts suggest moderation in consumption and recommend exploring natural alternatives such as honey, maple syrup, stevia, or monk fruit extract. A balanced diet rich in whole foods, combined with mental and physical activity, continues to be regarded as the best approach to maintaining long-term brain health.
